Methenolone enanthate – anabolic, modified dihydrotestosterone. It is characterized by the addition of a double bond between carbons 1 and 2, which helps to stabilize the 3-keto group and anabolic increases, the addition of 1-methyl group that protects against steroid metabolism in the liver. In use Primobolan depot enantatny ester attached to methenolone through 17-beta hydroxyl group (17b-hydroxy-1-methyl-5a-androst-1-en-3-one), the chemical formula C20H30O2. Esterified steroids are not as polar as free, they are absorbed less quickly from the injection site. Once in the bloodstream, and the ether is cleaved in the blood is free methenolone.
The development objective of esterified steroids were an extension of the therapeutic effect after the injection, injection is not able to exercise as often when compared with injections of steroids available. Enantatny ester is used to slow the absorption. Methenolone enanthate absorbed into the blood for a couple of weeks. Methenolone – a mild anabolic steroid, it has low androgenic, no estrogen. It is believed that the anabolic effect had slightly less than that of nandrolone. In cases where it is necessary to increase the amount of muscle and increase dryness on drying, it is advisable to apply the active drug.
First time methenolone described in 60. On the US market drugs sold by prescription, it has put the company under the name of Squibb methenolone enanthate in ’62, and then some time to sell under the name Nibal® Depot. In the same year the firm Schering in West Germany, acquired the rights to the drug, and Nibal® Depot quickly disappeared from the market. Schering began selling methenolone enanthate under a different trade name, soon became highly recognizable – Primobolan® Depot. Starting from the 60th year to the end of the 70s Primobolan® Depot was widely available in European countries such as Switzerland, Italy, Germany, Austria, Belgium, France, Portugal and Greece.
The patent for the drug company Schering belonged to late 70s. By the end of the patent term Schering stood on protecting their intellectual property from any potential threats, including the US market, and there is not even the drug was introduced. Despite the fact that methenolone enanthate decades absent from commercially available in the United States, at a technical level its status was restored after consultation with the FDA.
This allowed doctors from the United States to import Primobolan Depot for patients. A private joint pharmaceutical company has decided to resume the production of a generic drug. Currently, it is available by prescription only specialist who present the appropriate certification. Primobolan Depot is most often referred to as anabolic steroids which increase the dry weight of muscle. Quite often it is used when muscle loss was a consequence of operations buy primobolan uk, long-term infection, severe illness, corticosteroid drugs overdose or during recovery. Some doctors prescribe a drug for the treatment of osteoporosis, sarcopenia (age-natural muscle loss), isolated cases of chronic hepatitis and breast cancer (mainly as a complement when other therapy).
In addition, a steroid used to increase muscle growth in preterm infants and underweight children in clinical cases. As a result of studies, it was concluded that the drug have high efficiency, and any signs of toxicity, or side effects are absent. The drug is widely applicable and value among athletes as a combination of a strong anabolic, a weak androgen and non-estrogen. This makes it possible to achieve growth of lean muscle mass, without causing any side effects. Regardless of the fact that Primobolan clinical efficacy, Schering decided to withdraw from almost all of its sales markets. In the back there is no variation of 50 mg of the drug, but selective products containing 5 and 15 mg of the substance, there is still the opportunity to meet. There is only one certified source Primobolan oral drug and it is currently in Japan and South Africa. Regardless of the unavailability of the drug generic levitra, it is the only producer of Schering metenolone acetate worldwide. This is directly related to the time when the company is so eager to defend their rights to the drug for a long time.
Methenolone enanthate – synthetic derivative digirotestosterona, anabolic drugs prolonged action. It promotes protein synthesis in the body, inhibits nitrogen, calcium, sodium, potassium, chloride and phosphorus. This in turn leads to an increase in muscle mass and the acceleration of bone growth (in therapeutic doses) increases muscle dry weight. Often used in cases where the loss of muscle mass was the result of operations, long-term infection, severe disease, overdose of corticosteroids or in the recovery period. In preparation low androgenic activity.
Men 400-600 mg for 7 days; Women 100 mg for 7 days.
Men 100mg a day; Women 50 mg per day
Using the drug for medical purposes, is considered to be a maximum dose of 200mg daily. Standratnaya dose for improving body – 400-600 mg per day for 6-12 weeks. This dose is sufficient for the appearance of sensitive anabolic effect, but expect a large growth of the mass should not be. At doses of 600 mg and above, there are very noticeable side effects. Primabolan good use for the purpose of drying. Due to the mild action Primobolan, it is usually combined with other drugs. On drying combined with Halotestin or trenbolone. Such a mixture increases the volume of the muscles and improves their appearance in general. In competing athletes are not widely used combination of flavoring agents. In addition, it is used in combination frank zane now with testosterone or boldenone courses, whose purpose is to set the masses.
For women, there are restrictions when taking Primobolan. Not recommended for use during pregnancy and immediately before conception. Athlete may be used in 50-100mg without signs of virilization. Should not expect instantaneous weight gain, it will be a slow but steady. Some women are recommended to take in combination with primabolan Turinabol (10 mg daily) or oxandrolone (10-20mg per day), to increase the effectiveness of the course. Then we must be sure that the total dose will not be very high.
Methenolone attributed to anabolic androgenic but the likelihood of side effects is present. This may be an increased level of oily skin, acne, hair growth on the body and face. It is possible that the cause of their appearance will be a high level of received doses. Anabolic steroids can lead to deterioration of loss of hair of male type. It is to remind women about the likely effects of AAS virilizuyuschih: deepening of the voice, irregular periods, changes in the structure of the skin, facial hair growth, and clitoral enlargement. Methenolone is very mild steroid significant androgenic side effects can occur only at high doses. Women are often used to improve the body methenolone.
Methenolone is not classified as hepatotoxic drugs. If research has not been able to cause noticeable abnormalities in hepatic parameters, stress, taking the drug at therapeutic doses. At present there is some steroid ability to resist metabolism by the liver. It has been a case of death from liver failure in elderly patients who took the drug, but it is possible that this is the only case.
AAS can have adverse effects on blood cholesterol. For example, reduction of the “good” HDL cholesterol, shift the balance towards the risk of atherosclerosis. Relative impact AAS lipids is dependent on the dose, the route of entry, steroid type and level of resistance to hepatic metabolism. Methenolone have a stronger negative effect on the hepatic management of cholesterol than testosterone and nandrolone, since he had no flavoring structure, but the effect is not as strong as that of 17-alpha alkylated drugs. AAS can have an adverse effect on blood pressure and triglycerides, reduce relaxation of vascular endothelium, cause hypertrophy of the heart ventricles resolution fitness, which potentially increases the risk of cardiovascular disease and stroke. To reduce the load on the cardiovascular system, it is advised to minimize the intake of saturated fat, cholesterol, and simple carbohydrates during the course of the AAC. It is also recommended to take supplements, such as fish oil, lipid Stabil and similar products.
All AAS in doses which are necessary for building muscle, leading to inhibition of endogenous testosterone production. If you do not use testosterone stimulating drugs, testosterone come to your usual level for 1-4 months after the course. It is noted that prolonged application of hypogonadotrophic hypogonadism can develop into secondary and there is a risk that require medical intervention. Primobolan depot, if it is taken at a dose of 100-200mg little effect on the endogenous production of testosterone. Inhibition of testosterone during use methenolone may be weaker than with other drugs. It is possible that a long period of recovery after a course may not be required.
Loss of muscle mass after operations, long-term infection, severe disease, overdose of corticosteroids or in the recovery period. Sarcopenia (age-natural muscle loss), some cases of chronic hepatitis and breast cancer (mostly as an adjunct in the treatment of another); increase muscle growth in preterm infants and underweight children in clinical cases.
Nephrotic syndrome; prostate cancer; acute or chronic prostatitis; breast cancer in men; severe liver damage, liver failure supplements information in patients with cancer or liver metastases; Pregnancy and breast-feeding; hypersensitivity to any component of the drug.
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